Responses to faecal microbiota transplantation in female and male patients with irritable bowel syndrome.

ABSTRACT:

Background

Faecal microbiota transplantation (FMT) seems to be a promising treatment for irritable bowel syndrome (IBS) patients. In Western countries (United States and Europe), there is a female predominance in IBS. A sex difference in the response to FMT has been reported recently in IBS patients.

Aim

To investigate whether there was a sex difference in the response to FMT in the IBS patients who were included in our previous randomized controlled trial of the efficacy of FMT.

Methods

The study included 164 IBS patients who participated in our previous randomized controlled trial. These patients had moderate-to-severe IBS symptoms belonging to the IBS-D (diarrhoea-predominant), IBS-C (constipation-predominant) and IBS-M (mixed) subtypes, and had not responded to th

SUBMITTER: El-Salhy M 

PROVIDER: S-EPMC8117742 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature