Delayed anticoagulation in venous thromboembolism: Reasons and associated outcomes.

ABSTRACT:

Objective

We assessed the number of cases with delayed anticoagulation initiation, explored the reasons for the delay, and its impact on outcome in patients with acute venous thromboembolism (VTE) treated in an organized setting of treatment initiation and continuous, prospective follow-up.

Methods

Patients with anticoagulation initiation delay >24 hours were identified within the cohort of patients with acute VTE enrolled in the Mayo Clinic Venous Thromboembolism Registry between 2013 and 2020. The reasons for treatment delay were explored by reviewing the electronic database. VTE recurrence, all-cause mortality, major bleeding, and clinically relevant nonmajor bleeding (CRNMB) were compared to those with no anticoagulation delay.

Results

Of 2378 patients with acute

SUBMITTER: Brunton NE 

PROVIDER: S-EPMC8117818 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature