Development of a Microplate Platform for High-Throughput Sample Preparation Based on Microwave Metasurfaces.

ABSTRACT: Sample preparation is one of the most time-consuming steps in diagnostic assays, particularly those involving biological samples. In this paper we report the results of finite-difference time-domain (FDTD) simulations and thermographic imaging experiments carried out with the intent of designing a microplate for rapid, high-throughput sample preparation to aid diagnostic assays. This work is based on devices known as microwave lysing triangles (MLTs) that have been proven capable of rapid sample preparation when irradiated in a standard microwave cavity. FDTD software was used to model a microplate platform as a polystyrene substrate with an array of various passive scattering elements (PSEs) of different sizes, shapes, and interelement spacings in a 2.45 GHz field identical to that of a c

SUBMITTER: Nichols ZE 

PROVIDER: S-EPMC8117924 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature