Robust Carbonated Structural Color Barcodes with Ultralow Ontology Fluorescence as Biomimic Culture Platform.

ABSTRACT: Photonic crystal (PC) barcodes are a new type of spectrum-encoding microcarriers used in multiplex high-throughput bioassays, such as broad analysis of biomarkers for clinical diagnosis, gene expression, and cell culture. Unfortunately, most of these existing PC barcodes suffered from undesired features, including difficult spectrum-signal acquisition, weak mechanical strength, and high ontology fluorescence, which limited their development to real applications. To address these limitations, we report a new type of structural color-encoded PC barcodes. The barcodes are fabricated by the assembly of monodisperse polydopamine- (PDA-) coated silica (PDA@SiO₂) nanoparticles using a droplet-based microfluidic technique and followed by pyrolysis of PDA@SiO₂ (C@SiO₂

SUBMITTER: Liu P 

PROVIDER: S-EPMC8118130 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature