Gut microbiome differences among Mexican Americans with and without type 2 diabetes mellitus.

ABSTRACT:

Purpose

Type 2 diabetes mellitus (T2DM) is an urgent public health problem and disproportionately affects Mexican Americans. The gut microbiome contributes to the pathophysiology of diabetes; however, no studies have examined this association in Mexican-Americans. The objective of this study was to compare gut microbiome composition between Mexican-Americans with and without T2DM.

Methods

This was a cross-sectional study of volunteers from San Antonio, TX. Subjects were 18 years or older and self-identified as Mexican American. Subjects were grouped by prior T2DM diagnosis. Eligible subjects attended a clinic visit to provide demographic and medical information. Thereafter, subjects recorded their dietary intake for three days and collected a stool sample on the fourth day.

SUBMITTER: Kitten AK 

PROVIDER: S-EPMC8118452 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature