Common genetic variants associated with obesity in an African-American and Hispanic/Latino population.

ABSTRACT:

Introduction

Over 35% of all adults in the world are currently obese and risk of obesity in racial or ethnic minority groups exist in the US, but the causes of these differences are not all known. As obesity is a leading cause of cardiovascular disease, an improved understanding of risk factors across racial and ethnic groups may improve outcomes.

Objective

The objective of this study was to determine if susceptibility to obesity is associated with genetic variation in candidate single nucleotide polymorphisms (SNPs) in African Americans and Hispanic/Latinos.

Materials and methods

We examined data from 534 African Americans and 557 Hispanic/Latinos participants from the UIC Cohort of Patients, Family and Friends. Participants were genotyped for the top 26 obesity-asso

SUBMITTER: Chalazan B 

PROVIDER: S-EPMC8118531 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature