Performance characteristics of the Abbott Alinity m SARS-CoV-2 assay.

ABSTRACT: Mass molecular diagnostic testing for the SARS-CoV-2 pandemic has drawn on laboratory developed tests, commercial assays, and fully-automated platforms to accommodate widespread demand. The Alinity m instrument by Abbott is capable of detecting several clinically relevant pathogens and has recently received FDA emergency use authorization for SARS-CoV-2 molecular testing. The Alinity m performs automatic sample preparation, RT-PCR assembly, amplification, detection, and result calculation in under two hours. Here, we validate the performance characteristics of the Alinity m SARS-CoV-2 assay in comparison with the Roche cobas 6800 and Hologic Panther Fusion platforms. Across 178 positive and 195 negative nasopharyngeal swab specimens (C_T range 14.30-38.84), the Alinity m detected

SUBMITTER: Perchetti GA 

PROVIDER: S-EPMC8118701 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature