Molecular Biology in the Breast Clinics-Current status and future perspectives.

ABSTRACT: Breast cancer is no longer considered a single disease, and with better understanding of cancer biology, its management has evolved over the years, into a complex individualized use of therapeutics based on variable expressions of predictive and prognostic factors. With the advent of molecular and genetic research, the complexity and diversity of breast cancer cells and their ability to survive and develop resistance to treatment strategies became more evident. At the same time, targeted therapies evolved, as specific targets were discovered such as HER2 receptor, and androgen receptor. More recent is the development of immunotherapy which aims at strengthening the host immune system to identify and kill the tumor cells. In breast cancer treatment, use of molecular tests has been a target

SUBMITTER: Parmar V 

PROVIDER: S-EPMC8119514 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature