FMRI as an outcome measure in clinical trials: A systematic review in clinicaltrials.gov.

ABSTRACT:

Introduction

More than one-thousand trials with functional magnetic resonance imaging (fMRI) as an outcome measure were registered in clinicaltrials.gov at the time of writing this article. However, 93% of these registered trials are still not completed with published results and there is no picture available about methodological dimensions of these ongoing trials with fMRI as an outcome measure.

Methods

We collected trials that use fMRI as an outcome measure in the ClinicalTrials.gov registry on 13 October 2018 and reviewed each trial's record entry. Eligible trials' characteristics were extracted and summarized.

Results

In total, 1,386 clinical trials were identified that reported fMRI in their outcome measures with fMRI as the only primary outcome in 33% of them. 8

SUBMITTER: Sadraee A 

PROVIDER: S-EPMC8119793 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature