Separating scale-free and oscillatory components of neural activity in schizophrenia.

ABSTRACT:

Introduction

Alterations in narrow-band spectral power of electroencephalography (EEG) recordings are commonly reported in patients with schizophrenia (SZ). It is well established however that electrophysiological signals comprise a broadband scale-free (or fractal) component generated by mechanisms different from those producing oscillatory neural activity. Despite this known feature, it has not yet been investigated if spectral abnormalities found in SZ could be attributed to scale-free or oscillatory brain function.

Methods

In this study, we analyzed resting-state EEG recordings of 14 SZ patients and 14 healthy controls. Scale-free and oscillatory components of the power spectral density (PSD) were separated, and band-limited power (BLP) of the original (mixed) PSD, as we

SUBMITTER: Racz FS 

PROVIDER: S-EPMC8119820 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature