How biopsychosocial depressive risk shapes behavioral and neural responses to social evaluation in adolescence.

ABSTRACT:

Introduction

Understanding the emotional responsivity style and neurocognitive profiles of depression-related processes in at-risk youth may be helpful in revealing those most likely to develop affective disorders. However, the multiplicity of biopsychosocial risk factors makes it difficult to disentangle unique and combined effects at a neurobiological level.

Methods

In a population-derived sample of 56 older adolescents (aged 17-20), we adopted partial least squares regression and correlation models to explore the relationships between multivariate biopsychosocial risks for later depression, emotional response style, and fMRI activity, to rejecting and inclusive social feedback.

Results

Behaviorally, higher depressive risk was associated with both reduced negative a

SUBMITTER: Stretton J 

PROVIDER: S-EPMC8119860 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature