Auricular Vagus Neuromodulation-A Systematic Review on Quality of Evidence and Clinical Effects.

ABSTRACT: Background: The auricular branch of the vagus nerve runs superficially, which makes it a favorable target for non-invasive stimulation techniques to modulate vagal activity. For this reason, there have been many early-stage clinical trials on a diverse range of conditions. These trials often report conflicting results for the same indication. Methods: Using the Cochrane Risk of Bias tool we conducted a systematic review of auricular vagus nerve stimulation (aVNS) randomized controlled trials (RCTs) to identify the factors that led to these conflicting results. The majority of aVNS studies were assessed as having "some" or "high" risk of bias, which makes it difficult to interpret their results in a broader context. Results: There is evidence of a modest decrease in hea

SUBMITTER: Verma N 

PROVIDER: S-EPMC8120162 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature