Influence of renal insufficiency pre-heart transplantation on malignancy risk post-heart transplantation.

ABSTRACT:

Aims

Recent reports demonstrated that patients with heart failure (HF) might have an increased risk to develop malignancies. This is also seen in patients with chronic kidney disease (CKD). Immunosuppression in heart transplantation (HT) recipients additionally increases the risk of malignancies. The aim of this study was to determine the relation between HF duration and CKD pre-HT and the risk of malignancy development post-HT.

Methods and results

We included all adult HT recipients transplanted between January 2000 and November 2017 in our centre. Patients were excluded if they died or were retransplanted within 3 months post-HT. Clinical characteristics were retrospectively collected. Sixty out of 250 patients (24%) developed a malignancy after a median of 66 months [inte

SUBMITTER: Roest S 

PROVIDER: S-EPMC8120392 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature