Risk stratification with echocardiographic biomarkers in heart failure with preserved ejection fraction: the media echo score.

ABSTRACT:

Aims

Echocardiographic predictors of outcomes in heart failure with preserved ejection fraction (HFpEF) have not been systematically or independently validated. We aimed at identifying echocardiographic predictors of cardiovascular events in a large cohort of patients with HFpEF and to validate these in an independent large cohort.

Methods and results

We assessed the association between echocardiographic parameters and cardiovascular outcomes in 515 patients with heart failure with preserved left ventricular (LV) ejection fraction (>50%) in the MEtabolic Road to DIAstolic Heart Failure (MEDIA) multicentre study. We validated out findings in 286 patients from the Karolinska-Rennes Prospective Study of HFpEF (KaRen). After multiple adjustments including N-terminal pro-brain na

SUBMITTER: Huttin O 

PROVIDER: S-EPMC8120404 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature