Baseline Infection Burden and Cognitive Function in Elders with Essential Tremor.

ABSTRACT:

Background

Patients with essential tremor (ET) have an increased risk of cognitive impairment, yet little is known about the predictors of cognitive decline in these patients. Exposures to infectious agents throughout the lifespan may impact the later development of cognitive impairment. For example, high Infection exposure has been associated with lower cognitive performance in Alzheimer's and Parkinson's disease. However, this predictor has not been examined in ET.

Objectives

To determine whether a higher baseline infection burden is associated with worse cognitive performance at baseline and greater cognitive decline over time in an ET cohort.

Method/design

160 elderly non-demented ET participants (80.0 ± 9.5 years) underwent an extensive cognitive evaluation at th

SUBMITTER: Iglesias-Hernandez D 

PROVIDER: S-EPMC8121006 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature