Shining a Light on Phenotypic Drug Discovery.

ABSTRACT: In this issue of Cell Chemical Biology, Seneviratne et al. (2020) combine photoaffinity labeling and quantitative chemical proteomics to identify the molecular target of a lead compound discovered from a phenotypic drug screen. Their work showcase the power of coupling a photoreactive group to screening hits for rapid target deconvolution.

SUBMITTER: Hsu KL 

PROVIDER: S-EPMC8121186 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature