Changes in the illness perceptions of patients with rheumatoid arthritis over the first year of methotrexate therapy.

ABSTRACT:

Objectives

To describe the illness perceptions of patients with RA over the first year of MTX treatment, and the association between illness perceptions and outcomes.

Methods

Data came from the Rheumatoid Arthritis Medication Study (RAMS), a UK multicentre cohort study of RA patients starting MTX for the first time. Patients were assessed at baseline, and at 6 and 12 months. Patients completed the Brief Illness Perception Questionnaire (B-IPQ) at each assessment, as well as other patient-reported outcomes (PROs). The inflammation score (2-component DAS28) was calculated. Subgroups of patients with similar trajectories across the eight (B-IPQ) items were identified using a latent class growth model. Predictors of group membership were identified using multinomial logistic reg

SUBMITTER: Gwinnutt JM 

PROVIDER: S-EPMC8121436 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature