Ontology highlight
ABSTRACT:
SUBMITTER: Konig KC
PROVIDER: S-EPMC8121825 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
König Karl C KC Lahm Harald H Dreßen Martina M Doppler Stefanie A SA Eichhorn Stefan S Beck Nicole N Kraehschuetz Kathrin K Doll Sophia S Holdenrieder Stefan S Kastrati Adnan A Lange Rüdiger R Krane Markus M
Scientific reports 20210514 1
Acute type A aortic dissection (ATAAD) constitutes a life-threatening aortic pathology with significant morbidity and mortality. Without surgical intervention the usual mortality rate averages between 1 and 2% per hour. Thus, an early diagnosis of ATAAD is of pivotal importance to direct the affected patients to the appropriate treatment. Preceding tests to find an appropriate biomarker showed among others an increased aggrecan (ACAN) mRNA expression in aortic tissue of ATAAD patients. As a cons ...[more]