Age-related differences in resting-state and task-based network characteristics and cognition: a lifespan sample.

ABSTRACT: Aging is often associated with cognitive and neural decline, but how these factors interact is still not fully understood. Recently, functional connectivity, or the degree to which brain regions are concurrently active, has provided insight into age-related differences. However, functional connectivities during task and rest differ and few studies have examined how these relate to a broad range of cognitive functions. The present study investigated the effect of age on cognition, whole-brain functional connectivity during resting-state and task, and their relationships across the adult lifespan. Cognition was broadly assessed using a battery of cognitive assessments and mean network characteristics were calculated across the whole brain. Behaviorally, increased age was associated with wors

SUBMITTER: Zhang H 

PROVIDER: S-EPMC8122017 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature