Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception.

ABSTRACT: Many different forms of hormonal contraception are used by millions of women worldwide. These contraceptives differ in the dose and type of synthetic progestogenic compound (progestin) used, as well as the route of administration and whether or not they contain estrogenic compounds. There is an increasing awareness that different forms of contraception and different progestins have different side-effect profiles, in particular their cardiovascular effects, effects on reproductive cancers and susceptibility to infectious diseases. There is a need to develop new methods to suit different needs and with minimal risks, especially in under-resourced areas. This requires a better understanding of the pharmacokinetics, metabolism, serum and tissue concentrations of progestins used in contraceptio

SUBMITTER: Bick AJ 

PROVIDER: S-EPMC8122039 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature