Prospects for the Personalized Multimodal Therapy Approach to Pain Management via Action on NO and NOS.

ABSTRACT: Chronic pain syndromes are an important medical problem generated by various molecular, genetic, and pathophysiologic mechanisms. Back pain, neuropathic pain, and posttraumatic pain are the most important pathological processes associated with chronic pain in adults. Standard approaches to the treatment of them do not solve the problem of pain chronicity. This is the reason for the search for new personalized strategies for the prevention and treatment of chronic pain. The nitric oxide (NO) system can play one of the key roles in the development of peripheral pain and its chronicity. The purpose of the study is to review publications devoted to changes in the NO system in patients with peripheral chronical pain syndromes. We have carried out a search for the articles published in e-Library

SUBMITTER: Shnayder NA 

PROVIDER: S-EPMC8122598 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature