Association of MACROD2 gene variants with obesity and physical activity in a Korean population.

ABSTRACT:

Background

Obesity is a serious and common complex disease caused by the influence of genetic and environmental factors. Therefore, we aimed to evaluate the effect of genetic variants on obesity and the possibility of preventing obesity through physical activity using association analysis.

Methods

This study analyzed the association between obesity and variants in the MACROD2 gene in the Korean association resource (KARE) cohort using logistic regression analysis. Linear regression analysis was performed for obesity-related phenotype traits including body mass index (BMI), body fat percentage (BFP), abdominal fat percentage (AbFP), and the waist-to-hip ratio (WHR). The level of physical activity was analyzed by dividing the participants into two groups according to the cutof

SUBMITTER: Kim HR 

PROVIDER: S-EPMC8123725 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature