Effect of information on prostate biopsy history on biopsy outcomes in the era of MRI-targeted biopsies.

ABSTRACT:

Purpose

To describe the predictive value of information on previous benign biopsy for the outcome of MRI-targeted biopsies.

Methods

An exploratory analysis was conducted using data from a prospective, multicenter, paired diagnostic study of 532 men undergoing diagnostics for prostate cancer during 2016-2017. All men underwent 1.5 T MRI; systematic prostate biopsies; and MRI-targeted biopsies to MRI lesions with Prostate Imaging Reporting and Data System version 2, PI-RADS ≥ 3. The main outcome was numbers of detected prostate cancer characterized by grade group (GG) where GG ≥ 2 defined clinically significant cancer (csPCa).

Results

Men with previous biopsies had significantly more often negative MRI (26% vs. 17%, p < 0.05) compared to men without previous biopsies. M

SUBMITTER: Lantz A 

PROVIDER: S-EPMC8124045 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature