Prevention of Urinary Stones With Hydration (PUSH): Design and Rationale of a Clinical Trial.

ABSTRACT:

Rationale & objective

Although maintaining high fluid intake is an effective low-risk intervention for the secondary prevention of urinary stone disease, many patients with stones do not increase their fluid intake.

Study design

We describe the rationale and design of the Prevention of Urinary Stones With Hydration (PUSH) Study, a randomized trial of a multicomponent behavioral intervention program to increase and maintain high fluid intake. Participants are randomly assigned (1:1 ratio) to the intervention or control arm. The target sample size is 1,642 participants.

Setting & participants

Adults and adolescents 12 years and older with a symptomatic stone history and low urine volume are eligible. Exclusion criteria include infectious or monogenic causes of urinary s

SUBMITTER: Scales CD 

PROVIDER: S-EPMC8124076 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature