Surgery shows survival benefit in patients with primary intestinal diffuse large B-cell lymphoma: A population-based study.

ABSTRACT:

Background

The clinical characteristics and prognosis of primary intestinal diffuse large B-cell lymphoma (PI-DLBCL) are rarely reported. We aimed to explore the role of surgery in patients with PI-DLBCL.

Methods

Adult PI-DLBCL patients were included from the Surveillance, Epidemiology, and End Results database. The effect of surgery was evaluated by Kaplan-Meier and Cox proportional regression analyses. Propensity score matching (PSM) was used to reinforce our results. Lasso regression was utilized to determine independent risk factors of overall survival (OS) for a nomogram and a novel web-based calculator. The performance of the model was measured via concordance index, receiver operating characteristic curve, and calibration plots in both cohorts.

Results

Overall,

SUBMITTER: Wang M 

PROVIDER: S-EPMC8124121 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature