A Crucial Role of Mitochondrial Dynamics in Dehydration Resistance in Saccharomyces cerevisiae.

ABSTRACT: Mitochondria are dynamic organelles as they continuously undergo fission and fusion. These dynamic processes conduct not only mitochondrial network morphology but also activity regulation and quality control. Saccharomyces cerevisiae has a remarkable capacity to resist stress from dehydration/rehydration. Although mitochondria are noted for their role in desiccation tolerance, the mechanisms underlying these processes remains obscure. Here, we report that yeast cells that went through stationary growth phase have a better survival rate after dehydration/rehydration. Dynamic defective yeast cells with reduced mitochondrial genome cannot maintain the mitochondrial activity and survival rate of wild type cells. Our results demonstrate that yeast cells balance mitochondrial fusion and fission

SUBMITTER: Chen CL 

PROVIDER: S-EPMC8124315 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature