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Alkaloids of the Genus Datura: Review of a Rich Resource for Natural Product Discovery.


ABSTRACT: The genus Datura (Solanaceae) contains nine species of medicinal plants that have held both curative utility and cultural significance throughout history. This genus' particular bioactivity results from the enormous diversity of alkaloids it contains, making it a valuable study organism for many disciplines. Although Datura contains mostly tropane alkaloids (such as hyoscyamine and scopolamine), indole, beta-carboline, and pyrrolidine alkaloids have also been identified. The tools available to explore specialized metabolism in plants have undergone remarkable advances over the past couple of decades and provide renewed opportunities for discoveries of new compounds and the genetic basis for their biosynthesis. This review provides a comprehensive overview of studies on the alkaloids of Dat

SUBMITTER: Cinelli MA 

PROVIDER: S-EPMC8124590 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature