Anti-Thrombogenicity Study of a Covalently-Attached Monolayer on Stent-Grade Stainless Steel.

ABSTRACT: Implantable devices fabricated from austenitic type 316L stainless steel have been employed significantly in medicine, principally because the material displays excellent mechanical characteristics and corrosion resistance. It is well known, however, that interaction of exposure of such a material to blood can initiate platelet adhesion and blood coagulation, leading to a harmful medical condition. In order to prevent undesirable surface platelet adhesion on biomaterials employed in procedures such as renal dialysis, we developed an ultrathin anti-thrombogenic covalently attached monolayer based on monoethylene glycol silane chemistry. This functions by forming an interstitial hydration layer which displays restricted mobility in the prevention of surface fouling. In the present work, the

SUBMITTER: Yang T 

PROVIDER: S-EPMC8125229 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature