Ontology highlight
ABSTRACT:
SUBMITTER: Pontemezzo E
PROVIDER: S-EPMC8125323 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Pontemezzo Elena E Foglio Eleonora E Vernucci Enza E Magenta Alessandra A D'Agostino Marco M Sileno Sara S Astanina Elena E Bussolino Federico F Pellegrini Laura L Germani Antonia A Russo Matteo Antonio MA Limana Federica F
International journal of molecular sciences 20210507 9
Recent findings suggest that epithelial to mesenchymal transition (EMT), a key step during heart development, is involved in cardiac tissue repair following myocardial infarction (MI). MicroRNAs (miRNAs) act as key regulators in EMT processes; however, the mechanisms by which miRNAs target epicardial EMT remain largely unknown. Here, by using an <i>in vitro</i> model of epicardial EMT, we investigated the role of miRNAs as regulators of this process and their potential targets. EMT was induced i ...[more]