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Tripodal, Squaramide-Based Ion Pair Receptor for Effective Extraction of Sulfate Salt.

ABSTRACT: Combining three features-the high affinity of squaramides toward anions, cooperation in ion pair binding and preorganization of the binding domains in the tripodal platform-led to the effective receptor 2. The lack of at least one of these key elements in the structures of reference receptors 3 and 4 caused a lower affinity towards ion pairs. Receptor 2 was found to form an intramolecular network in wet chloroform, which changed into inorganic-organic associates after contact with ions and allowed salts to be extracted from an aqueous to an organic phase. The disparity in the binding mode of 2 with sulfates and with other monovalent anions led to the selective extraction of extremely hydrated sulfate anions in the presence of more lipophilic salts, thus overcoming the Hofmeister series.

SUBMITTER: Jagleniec D

PROVIDER: S-EPMC8125518 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Tripodal, Squaramide-Based Ion Pair Receptor for Effective Extraction of Sulfate Salt.

Jagleniec Damian D Wilczek Marcin M Romański Jan J

Molecules (Basel, Switzerland) 20210507 9

Combining three features-the high affinity of squaramides toward anions, cooperation in ion pair binding and preorganization of the binding domains in the tripodal platform-led to the effective receptor 2. The lack of at least one of these key elements in the structures of reference receptors 3 and 4 caused a lower affinity towards ion pairs. Receptor 2 was found to form an intramolecular network in wet chloroform, which changed into inorganic-organic associates after ...[more]

PMID: 34067071

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