Effects of thyroid-stimulating hormone suppression after thyroidectomy for thyroid cancer on bone mineral density in postmenopausal women: a systematic review and meta-analysis.

ABSTRACT:

Objectives

We assessed thyroid-stimulating hormone (TSH) suppression effects on bone mineral density (BMD) in postmenopausal women who underwent thyroidectomy.

Data sources

PubMed, EMBASE, Cochrane Library, Web of Science and SCOPUS were searched from inception to 24 February 2021.

Study selection

Case-control studies were included.

Data extraction and synthesis

Two authors independently reviewed the studies, extracted the data and performed meta-analysis of eligible studies.

Research design and methods

Studies evaluating BMD in postmenopausal women with thyroid cancer who had thyroidectomy and levothyroxine therapy were included. Differences in BMD were presented as standardised mean differences (SMDs). Meta-analyses were conducted using a random-effect

SUBMITTER: Kwak D 

PROVIDER: S-EPMC8126273 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature