Ontology highlight
ABSTRACT:
SUBMITTER: Kanth SM
PROVIDER: S-EPMC8126651 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Kanth Shreya M SM Gairhe Salina S Torabi-Parizi Parizad P
Frontiers in immunology 20210503
Semaphorins are a group of proteins that have been studied extensively for their critical function in neuronal development. They have been shown to regulate airway development, tumorigenesis, autoimmune diseases, and the adaptive immune response. Notably, emerging literature describes the role of immunoregulatory semaphorins and their receptors, plexins and neuropilins, as modulators of innate immunity and diseases defined by acute injury to the kidneys, abdomen, heart and lungs. In this review ...[more]