Novel SARS-CoV-2 variants: the pandemics within the pandemic.

ABSTRACT:

Background

Many new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater risk they pose due to possible enhanced transmissibility and/or severity, immune escape, diagnostic and/or treatment failure, and reduced vaccine efficacy.

Aims

We sought to review the current knowledge of emerging SARS-CoV-2 variants, particularly those deemed VOC/Is: B.1.351, B.1.1.7, and P.1.

Sources

MEDLINE and BioRxiv databases, as well as the grey literature, were searched for reports of SARS-CoV-2 variants since November 2020. Relevant articles and their references were screened.

Content

Mutations on the spike protein in particular may affect both affinity for the SARS-CoV-2 cell rec

SUBMITTER: Boehm E 

PROVIDER: S-EPMC8127517 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature