Does varying the ingestion period of sodium citrate influence blood alkalosis and gastrointestinal symptoms?

ABSTRACT:

Objectives

To compare blood alkalosis, gastrointestinal symptoms and indicators of strong ion difference after ingestion of 500 mg.kg-1 BM sodium citrate over four different periods.

Methods

Sixteen healthy and active participants ingested 500 mg.kg-1 BM sodium citrate in gelatine capsules over a 15, 30, 45 or 60 min period using a randomized cross-over experimental design. Gastrointestinal symptoms questionnaires and venous blood samples were collected before ingestion, immediately post-ingestion, and every 30 min for 480 min post-ingestion. Blood samples were analysed for blood pH, [HCO3-], [Na+], [Cl-] and plasma [citrate]. Linear mixed models were used to estimate the effect of the ingestion protocols.

Results

For all treatments, blood [HCO3-] was significantly el

SUBMITTER: Urwin CS 

PROVIDER: S-EPMC8128256 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature