The Association Between Arterial Oxygen Level and Outcome in Neurocritically Ill Patients is not Affected by Blood Pressure.

ABSTRACT:

Background

In neurocritically ill patients, one early mechanism behind secondary brain injury is low systemic blood pressure resulting in inadequate cerebral perfusion and consequent hypoxia. Intuitively, higher partial pressures of arterial oxygen (PaO₂) could be protective in case of inadequate cerebral circulation related to hemodynamic instability.

Study purpose

We examined whether the association between PaO₂ and mortality is different in patients with low compared to normal and high mean arterial pressure (MAP) in patients after various types of brain injury.

Methods

We screened the Finnish Intensive Care Consortium database for mechanically ventilated adult (≥ 18) brain injury patients treated in several tertiary intensive care units (ICUs

SUBMITTER: Humaloja J 

PROVIDER: S-EPMC8128839 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature