Dynamic Arterial Elastance Is Associated With the Vascular Waterfall in Patients Treated With Norepinephrine: An Observational Study.

ABSTRACT: Introduction: It has been suggested that dynamic arterial elastance (Ea_dyn) can predict decreases in arterial pressure in response to changing norepinephrine levels. The objective of this study was to determine whether Ea_dyn is correlated with determinants of the vascular waterfall [critical closing pressure (CCP) and systemic arterial resistance (SARi)] in patients treated with norepinephrine. Materials and Methods: Patients treated with norepinephrine for vasoplegia following cardiac surgery were studied. Vascular and flow parameters were recorded immediately before the norepinephrine infusion and then again once hemodynamic parameters had been stable for 15 min. The primary outcomes were Ea_dyn and its associations with CCP and SARi. The sec

SUBMITTER: Bar S 

PROVIDER: S-EPMC8129527 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature