Sensitivity to Thyroid Hormones and Risk of Prediabetes: A Cross-Sectional Study.

ABSTRACT:

Context

Thyroid hormone influences glucose homeostasis through central and peripheral regulations. To date, the link between sensitivity to thyroid hormones and prediabetes remains unknown. We aimed to investigate the association between thyroid hormones sensitivity and risk of prediabetes in both general and euthyroid populations.

Methods

Participants with serum free triiodothyronine (FT3), free thyroxine (FT4), and thyrotropin (TSH) measurements from the health checkup programs of the First Hospital of China Medical University were collected. We measured the parameters representing central and peripheral sensitivities to thyroid hormones (central sensitivity, assessed by calculating Thyroid Feedback Quantile-based Index (TFQI), TSH Index (TSHI), and Thyrotroph Thyroxine Re

SUBMITTER: Liu B 

PROVIDER: S-EPMC8129566 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature