Genome-wide detection of CNVs and their association with performance traits in broilers.

ABSTRACT:

Background

Copy number variations (CNVs) are a major type of structural genomic variants that underlie genetic architecture and phenotypic variation of complex traits, not only in humans, but also in livestock animals. We identified CNVs along the chicken genome and analyzed their association with performance traits. Genome-wide CNVs were inferred from Affymetrix® high density SNP-chip data for a broiler population. CNVs were concatenated into segments and association analyses were performed with linear mixed models considering a genomic relationship matrix, for birth weight, body weight at 21, 35, 41 and 42 days, feed intake from 35 to 41 days, feed conversion ratio from 35 to 41 days and, body weight gain from 35 to 41 days of age.

Results

We identified 23,214 autosomal CN

SUBMITTER: Fernandes AC 

PROVIDER: S-EPMC8130382 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature