Age-related trajectories of social cognition in youth at clinical high risk for psychosis: An exploratory study.

ABSTRACT:

Background

Clinical high risk (CHR) status is characterized by impairments in social cognition, but questions remain concerning their stability over development. In cross-sectional analysis of a large naturalistic sample, the current study examined whether those at CHR status show deviant trajectories for age-related change in social cognitive ability, and whether these trajectories are influenced by treatment history.

Method

Emotion perception (EP) and theory of mind (ToM) were assessed in 675 CHR and 263 healthy comparison (HC) participants aged 12-35. Age effects in CHR were modeled against HC age-expected performance. Prior medication status was tested for interactions with age.

Results

CHR exhibited normal age trajectory for EP, but significantly lower slopes for

SUBMITTER: Davidson CA 

PROVIDER: S-EPMC8130825 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature