Development of transfusion guidelines for injured children using a Modified Delphi Consensus Process.

ABSTRACT:

Background

There is wide variability of transfusion practices for children with hemorrhagic injuries across trauma centers. We are planning a multicenter, randomized clinical trial evaluating tranexamic acid in children with hemorrhage. Standardization of transfusion practices across sites is important to minimize confounding. Therefore, we sought to generate consensus-based transfusion guidelines for the trial.

Methods

We used a modified Delphi process utilizing a multi-site, multi-disciplinary panel of experts to develop our transfusion guidelines. A survey of 23 clinical categories on various aspects of transfusion practices was developed and distributed via SurveyMonkey®. Statements were graded on a 5-point Likert scale ("Strongly agree" to "This intervention may be harm

SUBMITTER: Trappey AF 

PROVIDER: S-EPMC8130983 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature