Prognostic models for knee osteoarthritis: a protocol for systematic review, critical appraisal, and meta-analysis.

ABSTRACT:

Background

Osteoarthritis is the most common degenerative joint disease. It is associated with significant socioeconomic burden and poor quality of life, mainly due to knee osteoarthritis (KOA), and related total knee arthroplasty (TKA). Since early detection method and disease-modifying drug is lacking, the key of KOA treatment is shifting to disease prevention and progression slowing. The prognostic prediction models are called for to guide clinical decision-making. The aim of our review is to identify and characterize reported multivariable prognostic models for KOA about three clinical concerns: (1) the risk of developing KOA in the general population, (2) the risk of receiving TKA in KOA patients, and (3) the outcome of TKA in KOA patients who plan to receive TKA.

Methods</

SUBMITTER: Zhong J 

PROVIDER: S-EPMC8131111 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature