Mouse prefrontal cortex represents learned rules for categorization.

ABSTRACT: The ability to categorize sensory stimuli is crucial for an animal's survival in a complex environment. Memorizing categories instead of individual exemplars enables greater behavioural flexibility and is computationally advantageous. Neurons that show category selectivity have been found in several areas of the mammalian neocortex^1-4, but the prefrontal cortex seems to have a prominent role^4,5 in this context. Specifically, in primates that are extensively trained on a categorization task, neurons in the prefrontal cortex rapidly and flexibly represent learned categories^6,7. However, how these representations first emerge in naive animals remains unexplored, leaving it unclear whether flexible representations are gradually built up as part of semantic memo

SUBMITTER: Reinert S 

PROVIDER: S-EPMC8131197 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature