The intergenerational interplay of adversity on salivary inflammation in young children and caregivers.

ABSTRACT: Systemic inflammation links exposure to early childhood adversity to later disease. The associations among adversity and disease risk might in part operate through poor oral hygiene and subsequent periodontal inflammation, which can be measured in saliva. Few studies, however, have examined the association between adversity and salivary inflammation in young children. Further, there is a dearth of literature investigating adverse experiences and salivary inflammation in children and caregivers together, limiting our understanding of the intergenerational, dual effects of adversity on inflammation for both members of the caregiver-child dyad. This study tested child and caregiver adversity and their associations with an inflammatory composite (i.e., IL-6, IL-1β, IL-8, TNF-α) and CRP in 93 p

SUBMITTER: Huffhines L 

PROVIDER: S-EPMC8131264 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature