Effect of antiepileptic drugs in glioma patients on self-reported depression, anxiety, and cognitive complaints.

ABSTRACT:

Introduction

AEDs have been associated with depression, anxiety, and cognitive impairment, all frequent complications of glioma and its subsequent treatment, with considerable morbidity and an adverse effect on health-related quality of life. This study aimed to determine the independent association between AED use and self-reported depression, anxiety, and subjective cognitive impairment in glioma patients.

Methods

In this multicenter cross-sectional study, depression and anxiety were assessed with the HADS and subjective cognitive impairment was assessed with the MOS-CFS. Univariable logistic regression analyses were performed on all potential confounding predictor variables. Potential confounders were included in the multivariable analyses if p-value < 0.1, to evaluate wh

SUBMITTER: van der Meer PB 

PROVIDER: S-EPMC8131297 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature