Coronavirus disease 2019 in heart transplant recipients: Risk factors, immunosuppression, and outcomes.

ABSTRACT:

Background

COVID-19 continues to inflict significant morbidity and mortality, particularly on patients with preexisting health conditions. The clinical course, outcomes, and significance of immunosuppression regimen in heart transplant recipients with COVID-19 remains unclear.

Methods

We included the first 99 heart transplant recipients at participating centers with COVID-19 and followed patients until resolution. We collected baseline information, symptoms, laboratory studies, vital signs, and outcomes for included patients. The association of immunosuppression regimens at baseline with severe disease were compared using logistic regression, adjusting for age and time since transplant.

Results

The median age was 60 years, 25% were female, and 44% were white. The medi

SUBMITTER: Genuardi MV 

PROVIDER: S-EPMC8131557 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature