Effect of hydroxychloroquine on COVID-19 prevention in cancer patients undergoing treatment: study protocol for a randomized controlled trial.

ABSTRACT:

Objectives

In this study, we will investigate the effect of hydroxychloroquine on the prevention of novel coronavirus disease (COVID-19) in cancer patients being treated.

Trial design

This is a two-arm, parallel-group, triple-blind, phase 2-3 randomized controlled trial.

Participants

All patients over the age of 15 years from 5 types of cancer will be included in the study. Patients with acute lymphoid and myeloid leukemias in the first line treated with curative intent, patients with high-grade non-Hodgkin's lymphoma treated with leukemia regimens, and patients with non-metastatic breast and colon cancer in the first line of treatment will enter the study.

Intervention and comparator

Patients are randomly assigned to two groups: one being given hydroxychloroqu

SUBMITTER: Rahimi H 

PROVIDER: S-EPMC8131879 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature