The Future of Neuroscience: Flexible and Wireless Implantable Neural Electronics.

ABSTRACT: Neurological diseases are a prevalent cause of global mortality and are of growing concern when considering an ageing global population. Traditional treatments are accompanied by serious side effects including repeated treatment sessions, invasive surgeries, or infections. For example, in the case of deep brain stimulation, large, stiff, and battery powered neural probes recruit thousands of neurons with each pulse, and can invoke a vigorous immune response. This paper presents challenges in engineering and neuroscience in developing miniaturized and biointegrated alternatives, in the form of microelectrode probes. Progress in design and topology of neural implants has shifted the goal post toward highly specific recording and stimulation, targeting small groups of neurons and reducing the

SUBMITTER: McGlynn E 

PROVIDER: S-EPMC8132070 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature