Chronic musculoskeletal impairment is associated with alterations in brain regions responsible for the production and perception of movement.

ABSTRACT:

Key points

Massive irreparable rotator cuff tear was used as a model to study the impact of chronic pain and motor impairment on the motor systems of the human brain using magnetic resonance imaging. Patients show markers of lower grey/white matter integrity and lower functional connectivity compared with control participants in regions responsible for movement and the perception of visual movement and body shape. An independent cohort of patients showed relative deficits in the perception of visual motion and hand laterality compared with an age-matched control group. These data support the hypothesis that the structure and function of the motor control system differs in patients who have experienced chronic motor impairment. This work also raises a new hypothesis, supported by ne

SUBMITTER: Conboy V 

PROVIDER: S-EPMC8132184 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature