Intergenerational Transmission of Frontal Alpha Asymmetry Among Mother-Infant Dyads.

ABSTRACT:

Background

Frontal alpha asymmetry (FAA) is a well-established neurobiological indicator of depression risk. Reduced FAA relates to current and remitted depression in adults and is seen in offspring of mothers with depression as young as 3 months of age, suggesting a potentially transmittable mechanism of depression risk. It is unclear, however, whether direct familial associations exist for FAA. To address this gap, we evaluated the intergenerational transmission of FAA in a nonclinical cohort of mother-infant dyads.

Methods

Mothers and their 12-month-old infants (n = 34 dyads) completed parallel resting-state tasks while electroencephalography was recorded. We measured FAA across a range of putative frequency bands and calculated its reliability in mothers and infants. Fin

SUBMITTER: Hill KE 

PROVIDER: S-EPMC8132443 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature