Distinct neuron phenotypes may serve object feature sensing in the electrosensory lobe of Gymnotus omarorum.

ABSTRACT: Early sensory relay circuits in the vertebrate medulla often adopt a cerebellum-like organization specialized for comparing primary afferent inputs with central expectations. These circuits usually have a dual output, carried by center ON and center OFF neurons responding in opposite ways to the same stimulus at the center of their receptive fields. Here, we show in the electrosensory lateral line lobe of Gymnotiform weakly electric fish that basilar pyramidal neurons, representing 'ON' cells, and non-basilar pyramidal neurons, representing 'OFF' cells, have different intrinsic electrophysiological properties. We used classical anatomical techniques and electrophysiological in vitro recordings to compare these neurons. Basilar neurons are silent at rest, have a high threshold to intracellu

SUBMITTER: Nogueira J 

PROVIDER: S-EPMC8132969 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature